It would seem that e-learning is finally taking its place in contributing to education for sustainable development in Africa. This study assesses e-learning for sustainability in sub-Sahara Africa by drawing on some case studies such as the African Virtual University. The assessment investigates the extent to which e-learning initiatives are home-grown, i.e. specifically designed to solve local problems, how e-learning is bridging the lack of human capacity, and access to information on sustainability. Moreover, it addresses the question of how inclusive e-learning for sustainability could be in Africa, especially in view of infrastructural limitations and the costs of participating in e-learning courses. The chapter concludes with some recommendations for future developments in e-learning for sustainability in Africa.